Advanced Cell Line Development & Bioprocess Technology: From Clone Selection to Commercial Manufacturing Readiness

Course Summary

The success of biologics manufacturing depends heavily on robust cell line development and scalable bioprocess strategies. Developing a high-performing production cell line requires integration of molecular engineering, clone screening, process optimisation, analytical characterisation and manufacturing considerations.

This one-day program provides a practical understanding of advanced cell line development and bioprocess technology, covering the journey from cell-line engineering and clone selection to upstream processing, downstream purification and commercial manufacturing readiness.

Participants explore how development teams optimise productivity, product quality, process robustness and scalability while managing challenges related to process variability, analytical characterisation and technology transfer.

The program focuses on practical industry applications, enabling participants to understand how scientific decisions during early development influence manufacturing performance and commercial success.

Who Should Attend

• Biologics R&D Scientists
• Cell Line Development Scientists
• Upstream Process Development Teams
• Downstream Process Development Teams
• MSAT Professionals
• Manufacturing Science Professionals
• CMC Teams
• Analytical Development Professionals
• Bioprocess Engineers
• R&D Leaders managing biologics development programs

Business Outcomes

Participants will be able to:

• Understand the end-to-end cell line development lifecycle.
• Evaluate key parameters influencing clone selection and productivity.
• Improve understanding of upstream and downstream process optimisation.
• Identify critical process parameters affecting product quality and yield.
• Connect development decisions with manufacturing scalability.
• Improve collaboration between R&D, MSAT and manufacturing teams.
• Recognise technology-transfer considerations during process development.